针对不同强度和持续时间的运动,急性唾液抗微生物分泌反应
Reita Ito1, Takamasa Uchino1, Masataka Uchida2,3
1Faculty of Sport and Health Science, Ritsumeikan University, Kusatsu, Japan.
概括
急性运动会影响唾液中的抗微生物,强度和持续时间会影响乳酸,人体β-防御素-2 (HBD-2) 和酶的水平. 一些呈现出多样化的反应,突出了炼运动.
科学领域:
- 运动免疫学 运动免疫学
- 具有先天性粘膜免疫力
- 口腔微生物组防御口腔微生物组防御
背景情况:
- 抗菌 (AMP) 对于口腔内先天性粘膜免疫至关重要,具有抗菌和细菌解毒性.
- 了解急性运动如何调节这些唾液AMP对于理解口腔免疫反应至关重要.
- 以前的研究还没有完全阐明运动强度和持续时间对特定唾液AMP的差异性影响.
研究的目的:
- 研究不同强度和持续时间的急性运动对健康年轻男性唾液抗菌水平的影响.
- 为了比较不同唾液AMP的分泌反应,包括乳二,人类β-防御素-2 (HBD-2),lyszyme和LL-37,以炼刺激.
- 为了确定运动强度或持续时间是否对这些关键口腔免疫成分的水平产生不同影响.
主要方法:
- 一个随机交叉试验,涉及14名健康,未受过训练的年轻男性.
- 参与者完成了不同强度 (35%,55%,75%V·o2max30分钟) 和持续时间 (55%V·o2max30分钟,60,90分钟) 的自行车试验.
- 唾液样本在基线收集,在运动后立即 (0分钟),并在运动后60分钟收集以测量AMP度.
主要成果:
- 较高的运动强度 (75%V·o2max) 与较低强度 (35%,55%) 相比,显著增加了唾液中乳酸和HBD-2水平.
- Salivary lysozyme在运动后增加,无论强度如何,而LL-37水平在所有强度试验中保持不变.
- 与30分钟相比,较长的运动持续时间 (60,90分钟) 在55%V·o2max导致LL-37和HBD-2的增加较大,而无论持续时间如何,乳酸和酶都增加了.
结论:
- 唾液抗微生物对急性运动的分泌反应因运动强度和持续时间而异.
- 乳酸,HBD-2和酶水平对急性运动刺激敏感,根据强度和持续时间表现出不同的反应.
- LL-37表现出明显的反应模式,随时间而增加,但不是强度,这表明口腔先天免疫的复杂调节机制.
相关概念视频
01:23Salivary Glands and Saliva
522
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
522
01:20Exercise and Cardiovascular Response
755
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
755
01:18Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
01:27Exercise and Muscle Performance
1.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.4K
01:17Exercise and Cardiac Output
950
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
950