[多种药物治疗的患者根据功能进行剂量调整,包括使用药物合规辅助器 (MCA) 的药物康复服务]
Damià Barris Blundell1, Homa Mousavi1
1Farmacéutico comunitario. Farmacia Zarzuelo, Benalmádena (Málaga). España.
Farmaceuticos comunitarios
|August 19, 2024
概括
一项药物审查发现,老年患者的功能下降 (eGFR) 会导致疲劳和困惑. 调整洛萨坦和曼尼迪平的剂量可以缓解这些症状,这凸显了功能在药物管理中的重要性.
科学领域:
- 老年医学 老年医学
- 临床药房 临床药房
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 多种药物治疗的老年患者有不良药物事件的风险.
- 降低功能可能导致药物积累和毒性.
- 疲劳,虚弱,头和困惑等症状可能表明老年人患有与药物相关的问题.
研究的目的:
- 调查估计的淋巴膜过率 (eGFR) 与多种药物治疗的老年患者的不良症状之间的潜在联系.
- 评估药物审查和剂量调整对患者报告的症状的影响.
- 强调在抗高血压药物管理中考虑功能的重要性.
主要方法:
- 对一名78岁的患者进行了全面的药物评估,该患者经历了新发的疲劳,虚弱,头和混乱.
- 估计的淋巴膜过率 (eGFR) 计算用于评估功能.
- 向初级保健医生 (PCP) 的转诊建议根据患者的eGFR减少洛萨坦和曼尼迪平的剂量.
主要成果:
- 患者的eGFR表明需要对脏排泄的药物进行剂量调整.
- 该PCP实施了推的降低抗高血压药物的剂量 (洛萨坦和曼尼迪平).
- 在剂量调整后,患者的疲劳,虚弱,头和困惑的症状消失了.
结论:
- 以eGFR为指导的药物评估对于管理多种药物治疗的老年患者至关重要.
- 根据功能对抗高血压药物的适当剂量调整可以有效地解决不良症状.
- 这一案例凸显了老年人药物治疗中个性化药物管理的重要性.
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