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使用SMART-REACH模型和印尼ASCVD患者的直接住院费用概况的复发性心血管事件风险估计:一项大型多中心研究

Bambang Dwiputra¹, Dwita Rian Desandri¹, Anggoro Budi Hartopo²

¹Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia-National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia.

Frontiers in cardiovascular medicine

|August 19, 2024

概括

印尼动脉样硬化心血管疾病 (ASCVD) 患者面临高风险的复发事件和显著的住院费用. 在SMART-REACH模型中发现了30.2%的10年风险和62.5%的终身风险,突出了优化二次预防疗法的需要.

科学领域:

心脏病学心脏病学
公共卫生公共卫生
卫生经济学卫生经济学

背景情况:

印度尼西亚不断增加的动脉样硬化心血管疾病 (ASCVD) 病例需要改善二次预防的风险分层.
关于印尼ASCVD患者的复发性心血管事件风险和直接住院费用,存在很大的数据缺口.
了解这些因素对于减少印尼与ASCVD相关的经济负担至关重要.

研究的目的:

用SMART-REACH模型估计印尼ASCVD患者心血管事件的10年和终身风险.
描述与印度尼西亚ASCVD相关的直接住院费用.
为优化二次预防治疗和减轻经济负担提供数据.

主要方法:

一项描述性的横截面研究,涉及3209名来自印度尼西亚两个主要心血管中心的ASCVD患者 (年龄在45-80岁).
收集的数据包括临床信息,入院后24小时内的实验室结果和出院药物.
风险估计使用了SMART-REACH模型,Fine和Grey竞争风险模型;从入院到出院的直接住院费用计算.

主要成果:

研究队列 (平均年龄60.15岁) 主要是男性 (79.1%) 和高血压患者 (70.6%),STEMI是最常见的诊断 (54%).
据SMART-REACH模型估计,复发性心血管事件的平均十年风险为30.2%,终身风险为62.5%.
ASCVD患者的直接住院成本中位数为3,033美元,而STEMI患者的中位数成本最高 (3,270美元).

结论:

印度尼西亚的ASCVD患者表现出10年和终身重大心血管事件的高风险.
与ASCVD相关的直接住院费用是相当大的.
治疗优化对于减轻这些风险和降低医疗保健系统的整体经济负担至关重要.

关键词:

动脉样硬化心血管疾病冠心病是一种冠心病.造价分析造价分析造价分析造价分析风险估计风险估计二次预防二次预防.

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