重新考虑胆囊切除术中的胆囊样本的常规组织病理检查:优化临床实践和资源管理
Zohaib Jamal1, Zirong Yu1, Nowera Zafar1
1Department of Surgery, Redland Hospital, Bayside Health Service, Redland, AUS.
Cureus
|August 19, 2024
概括
胆囊切除术后胆囊样本的常规组织病理学检查 (HPE) 可能不必对所有患者进行,特别是在胆囊癌 (GBC) 发病率低的地区. 基于宏观发现的选择性HPE可以具有成本效益,并且可以在不影响患者安全的情况下降低工作量.
科学领域:
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
- 在瘤学瘤学.
背景情况:
- 胆囊切除术是一种常见的程序,胆囊样本的常规组织病理学检查 (HPE) 是检测胆囊癌 (GBC) 的标准实践.
- 全球GBC发病率各不相同,影响了日常HPE的必要性和实践.
- 根据风险因素和资源可用性,可以考虑对标本进行选择性处理.
研究的目的:
- 评估胆囊切除术后所有胆囊样本是否需要例行HPE.
- 评估HPE的选择性方法,优先考虑患者安全和资源优化.
- 为了确定常规HPE在低GBC发病率环境中的实用性.
主要方法:
- 在澳大利亚雷德兰医院进行了一项回顾性队列研究,分析了2023年1月至12月期间从胆囊切除术中获得的266个胆囊样本.
- 数据包括人口统计数据,手术指标,手术内发现和组织病理学结果.
- 对样本进行了癌症病理学指标的审查,重点是偶然的胆囊癌 (IGC).
主要成果:
- 在检查的266个标本中,没有发现GBC病例.
- 总共有3.3% (9) 的标本显示出先发性病原体特征.
- 大多数手术 (56.4%) 是选择性腹腔镜胆囊切除术.
结论:
- 选择性HPE方法,专注于具有宏观异常的标本,在低GBC发病率地区似乎是谨慎的.
- 这一策略可以减少组织病理学工作量和成本,而不会影响患者的治疗结果.
- 在HPE提交之前,建议对胆囊切除术患者进行例行宏观检查,特别是那些患有胆结石疾病的患者.
相关概念视频
Gallbladder
439
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
439
Liver Histology
650
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Hepatocytes perform a variety of essential functions. They secrete...
650


