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Yue Yang1, Yi-Dan Luo1, Chen-Bo Zhang1

  • 1School of Medicine, Yan'an University, Yan'an 716000, China.

ACS omega
|August 19, 2024
PubMed
概括

本综述将SARS-CoV-2主要蛋白酶 (Mpro) 抑制剂分为模仿性,非模仿性和天然化合物. 它详细介绍了它们的机制,活动和进展,为开发新抗病毒药物对抗COVID-19提供了洞察力.

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Conjugated Proteins02:50

Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
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