生物流体中氧硫酸的分析,重点是样品制备技术:全面的分析审查
Samira Shafiee1,2,3, Siavoush Dastmalchi2,3, Afshin Gharekhani3
1Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Heliyon
|August 19, 2024
概括
尿路毒素硫酸 (IS) 与慢性病 (CKD) 有关. 测量生物流体中的IS有助于评估功能,样本准备对于准确的生物分析至关重要.
科学领域:
- 生物化学 生物化学
- 临床化学 临床化学
- 分析化学 分析化学
背景情况:
- 尿路毒素硫酸 (IS) 与慢性病 (CKD) 的进展和相关并发症有关.
- 精确量化生物流体中的IS对于监测功能和疾病严重程度至关重要.
- 内源矩阵组件可以干扰IS生物分析,需要有效的样本准备技术.
研究的目的:
- 审查生物样本中氧硫酸盐 (IS) 量化分析方法.
- 强调样本准备在IS准确生物分析中的关键作用.
- 提供有关临床诊断中IS评估当前方法的见解.
主要方法:
- 对IS检测分析技术的文献综述.
- 专注于样本准备策略,以减轻矩阵效应.
- 分析各种生物流体,包括血清,尿液和血.
主要成果:
- 多种分析技术,如LC,GC,光谱和电化学用于IS量化.
- 有效的样本准备方法对于减少干扰和提高测定灵敏度和特异性至关重要.
- 该审查整合了评估不同生物矩阵中的IS水平的研究结果.
结论:
- 硫酸 (IS) 是评估功能和CKD的一个重要的生物标志物.
- 分析方法的进步,特别是样品的准备,是可靠的IS生物分析的关键.
- 需要标准化和优化的样本准备协议,以实现IS量化的一致的诊断应用.
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