SARS-CoV-2作为年轻人微观结肠炎的潜在触发因素:一个病例报告
A Alwali1, C Schafmayer1, F Prall2
1Department of General, Visceral, Thorax, Vascular and Transplantation Surgery, Rostock University Medical Center, Rostock, Germany.
Heliyon
|August 19, 2024
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 可能引发淋巴细胞结肠炎,一种微观结肠炎的形式. 这项案例研究建议在COVID-19后患有持续性腹的患者中考虑这种诊断.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 持续的胃肠道 (GI) 症状,包括慢性腹和腹痛,可能发生在SARS-CoV-2感染后.
- 微观性结肠炎,特别是淋巴细胞性结肠炎,以淋巴细胞透结肠表皮为特征.
- 病毒感染与炎症疾病的发生之间的潜在联系是正在进行的研究领域.
研究的目的:
- 在SARS-CoV-2感染后报告慢性腹病例.
- 调查SARS-CoV-2在触发淋巴细胞结肠炎中的潜在作用.
- 强调在COVID-19后的胃肠道并发症中考虑微观结肠炎的重要性.
主要方法:
- 在SARS-CoV-2感染后,一名年轻成年人患有持续性腹和腹痛的病例报告.
- 进行了全面的实验室和成像检查.
- 进行了结肠镜检查和结肠活检,以评估结肠粘膜.
- 活检的组织病理学检查证实了淋巴细胞透.
主要成果:
- 广泛的调查没有显示出任何显著的发现,导致最初的诊断是刺激性肠综合征.
- 结肠镜检查显示结肠粘膜不显著,但活检证实了适度的淋巴细胞透与淋巴细胞结肠炎一致.
- 用布索尼德治疗导致症状完全消失.
结论:
- 感染SARS-CoV-2可能会引发淋巴细胞性结肠炎.
- 临床医生应考虑在SARS-CoV-2感染后患有持续性腹的患者中进行显微性结肠炎.
- 需要进一步的研究来阐明COVID-19后的胃肠道并发症的机制和患病率.
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