肌肉骨建模和运动模拟用于结构性关节疾病研究:方法,验证和应用的范围审查
Margaret S Harrington1, Stefania D F Di Leo1, Courtney A Hlady1,2
1Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Heliyon
|August 19, 2024
概括
本综述综合了关节疾病的肌肉骨建模方法. 它强调了模型选择,验证和可重复性的挑战,为研究人员提供了一个改善报告标准的模板.
科学领域:
- 生物力学 生物力学
- 肌肉骨系统的建模
- 整形外科 整形外科 整形外科
背景情况:
- 肌肉骨模型量化生物力学因素,如部接触力和肌肉激活.
- 进步增加了可访问性,但使病理群体的方法选择复杂化.
- 结构性部疾病涉及骨盆或大腿骨的骨异常.
研究的目的:
- 概述结构性关节疾病研究中的当前建模和模拟方法.
- 评估模型验证和研究可重复性.
- 为研究人员使用肌肉骨模型调查部疾病提供指导.
主要方法:
- 在 MEDLINE 和 Web of Science 的系统文献搜索.
- 分析了47篇文章,比较或应用肌肉骨建模工作流程.
- 评估模型验证实践和方法报告.
主要成果:
- 报告数据收集,处理和建模方法的变异性已确定.
- 观察到有限的验证实践;只有11项研究使用定性方法验证了模型.
- 在模型估计的部接触和基于建模技术 (通用与患者特定) 的肌肉力量中观察到的差异.
结论:
- 开发了一个模板,以提高可复制性方法的透明度和报告能力.
- 建模方法的综合有助于研究人员做出明智的决策和评估文献.
- 改善报告标准对于在关节疾病研究中推进肌肉骨建模至关重要.
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