在免疫能力强的患者中晚期假肢关节感染中的Candida护理症:一系列病例
James C George1, B Samuel Chittaranjan1, Subin Babu1
1Department of Orthopaedic Surgery, Believers Church Medical College Hospital, Pathanamthitta, Kerala, India.
Journal of orthopaedic case reports
|August 19, 2024
概括
在免疫能力强的人群中,真菌假肢关节感染 (PJIs) 是罕见的. 晚期出现的真菌PJIs可以通过除菌,扩展培养和长期抗真菌治疗成功管理,防止复发.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
背景情况:
- 性假肢关节感染 (PJIs) 不常见,特别是在免疫能力强的患者中.
- 晚期出现的真菌PJIs经常模仿无菌松动,由于病原体隔离的挑战,复杂的诊断.
- 目前缺乏针对这些具体案例的管理指南.
研究的目的:
- 报告5例由Candida parapsilosis引起的晚期慢性假肢关节感染病例的临床表现和管理情况.
- 为突出诊断挑战和治疗结果的真菌PJIs在免疫能力较强的个体.
主要方法:
- 五个免疫能力较强的患者的回顾性病例系列,培养负面,晚出现的真菌PJIs.
- 涉及广泛的手术除菌,精心的手术内抽样扩展的真菌培养.
- 治疗包括脱bridement后的长期抗真菌疗法.
主要成果:
- 所有五名患有晚期慢性PJI的患者均具有免疫能力,并在手术前培养阴性.
- 确定了三名膝盖和两名部半关节整形PJIs.
- 所有患者在用抗真菌药物治疗后的随访期间都取得了成功的结果,没有疾病的重新激活或复发.
结论:
- 在呈现无菌放松症状而没有典型感染迹象的免疫能力较强的患者中,应考虑真菌PJI.
- 手术修复与延长的抗真菌抑制疗法相结合,可以在管理晚期真菌PJIs方面产生有利的结果.
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