预后营养指数 (PNI):对于为逆皮质脂肉瘤进行手术的患者来说,更有前途的营养预测指数
Guo-Qiang Xue1, Cheng-Peng Li1, Ang Lv1
1Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Hepato-Pancreato-Biliary Surgery/Sarcoma Center, Peking University Cancer Hospital & Institute, Beijing, People's Republic of China.
Cancer management and research
|August 19, 2024
概括
营养状况显著影响 retroperitoneal 脂质肉瘤 (RLPS) 患者的结果. 预后营养指数 (PNI) 较低预测RLPS手术后的生存率较差和并发症增加.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 营养科学 营养科学
背景情况:
- 逆皮质脂肉瘤 (RLPS) 的治疗涉及到广泛的手术.
- 营养不良与RLPS患者的手术结果和生存率较差有关.
研究的目的:
- 评估RLPS患者营养状况的预后意义.
- 确定可靠的营养指标,以预测RLPS的结果.
主要方法:
- 189名接受手术的RLPS患者的回顾性审查.
- 营养指数的计算:营养风险指数,预后营养指数 (PNI) 和2002年营养风险查.
- 时间依赖的ROC曲线分析,以评估预后效用和与并发症和生存相关的关系 (LRFS,OS).
主要成果:
- 预后营养指数 (PNI) 在预测整体存活率 (OS) 中优越.
- 41.2的PNI切线确定了患者,其局部无复发生存期 (LRFS) 和OS显著较短.
- 低PNI (<41.2) 与较高的发病率,死亡率和较差的生存结果相关,独立于其他因素.
结论:
- 预后营养指数 (PNI) 是RLPS营养评估的一个有价值的工具.
- 较低的PNI是 retroperitoneal liposarcoma患者不良生存结果的重要预测因素.
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