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Updated: Jun 16, 2025

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Gpx4 通过防止脂质过氧化和铁死来调节不变NKT细胞的恒常性和功能

Sophia P M Sok1, Kaitlyn Pipkin1, Narcis I Popescu1

  • 1Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK.

Journal of immunology (Baltimore, Md. : 1950)
|August 19, 2024
PubMed
概括

不变的自然杀手T (iNKT) 细胞依赖谷氨过氧化酶4 (Gpx4) 防止脂质过氧化和铁亡. 缺乏Gpx4会损害iNKT细胞的功能和生存,突出显示了它在免疫平衡中的关键作用.

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