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患有2型糖尿病失控的老年患者中骨质沙丘病的患病率和危险因素
Tingying Xiao1, Shiyue Zou1, Ting Luo1
1Endocrinology Department, The First People's Hospital of Longquanyi District, Chengdu, Sichuan, China.
骨髓缩症在患有2型糖尿病的老年患者中很普遍. 男性性别,更低的禁食血葡萄糖和较低的尾骨肌肉质量指数是关键的危险因素.
科学领域:
- 老年学是指老年学的学科.
- 内分泌学 在内分泌学.
- 代谢疾病 代谢疾病
背景情况:
- 患有2型糖尿病 (T2DM) 的老年患者有患骨质疏松症 (OS) 的风险,骨质疏松症和骨质疏松症结合在一起的疾病.
- 了解这个人群中OS的患病率和风险因素对于有针对性的干预至关重要.
研究的目的:
- 为了确定患有2型糖尿病的住院老年患者中骨质疏松症的患病率.
- 在这个群体中确定与骨质沙症发展相关的风险因素.
主要方法:
- 一项涉及254名60岁及以上的住院T2DM患者的横截面研究.
- 评估包括骨矿物质密度 (BMD),握力,短物理性能电池 (SPPB) 和身体组成.
- 骨髓缩症的诊断是基于2019年亚洲骨髓缩症工作组 (AWGS) 的标准和骨质疏松症定义;后勤回归确定了危险因素.
主要成果:
- 在T2DM患者中,骨质石症的患病率为22.8% (58名患者).
- 男性性别 (OR:5.738),更低的禁食血葡萄糖 (OR:0.904),以及较低的尾骨肌肉质量指数 (ASMI) (OR:0.049) 与骨质疏松症显著相关.
- 老年人 (72.7岁) 的患病率高于没有OS的人 (69.3岁).
结论:
- 骨髓缩症是老年T2DM患者常见的疾病.
- 男性性别,低禁食血葡萄糖和低ASMI是该人群中骨髓缩症的重要危险因素.
- 进一步的研究和临床关注对于T2DM患者的OS管理是有必要的.
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