促进1型糖尿病青少年应激管理中的性:一项随机临床试验
Joyce P Yi-Frazier1,2, Marisa E Hilliard3, Maeve B O'Donnell1,4
1Center for Clinical & Translational Research, Seattle Children's Research Institute, Seattle, Washington.
促进应激管理中的弹性 (PRISM) 干预措施在12个月后改善了1型糖尿病 (T1D) 青少年的糖尿病困扰和自我管理行为. 虽然HbA1c水平没有显著变化,但PRISM显示出增强心理社会结果的前景.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 青少年心理学 青少年心理学
- 行为医学是一种行为医学.
背景情况:
- 1型糖尿病 (T1D) 管理需要青少年做出大量的自我照顾努力,青少年容易受到心理社会挑战和不良医疗结果的影响.
- 发展性技能可以使T1D青少年能够管理压力因素并改善整体幸福感.
研究的目的:
- 评估促进应激管理中的弹性 (PRISM) 干预措施的有效性.
- 评估PRISM对T1D青少年血红蛋白A1c (HbA1c),糖尿病困扰,自我管理行为,弹性和生活质量的影响.
主要方法:
- 一个第三阶段的随机临床试验,涉及172名青少年 (年龄13-18岁) 患有T1D和升高的痛苦.
- 参与者被随机分配1:1接受PRISM干预 (基于技能,辅导员辅导,使用数字应用程序) 或常规护理 (UC).
- 结果在基线,6个月和12个月使用线性混合效应回归模型进行评估.
主要成果:
- 在12个月后,在PRISM和UC组之间没有观察到HbA1c水平的显著差异.
- 与UC组相比,PRISM接受者报告说,与UC组相比,糖尿病困扰显著减少 (P=.01).
- 与UC相比,PRISM组的青少年在自我管理行为方面表现出显著的改善 (P=.01).
结论:
- PRISM干预措施在改善心理社会结果方面表现出有效性,特别是减少糖尿病困扰并增强T1D青少年的自我管理行为.
- 将弹性建设策略整合到糖尿病护理中,为改善面临T1D相关挑战的青少年的生活质量提供了有希望的方法.
- 进一步的研究应该探索长期影响和在儿科糖尿病护理中更广泛地实施基于优势的干预措施.
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