Fam49b抑制TCR信号强度,以调节积极选择的乳腺细胞和外围T细胞的存活率

相关实验视频

Updated: Jun 16, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
08:49

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Published on: January 22, 2019

9.1K

Chan-Su Park1,2, Jian Guan1, Peter Rhee1

  • 1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, United States.

eLife
|August 19, 2024
PubMed
概括

序列相似性49家族成员B (Fam49b) 抑制T细胞受体 (TCR) 信号传递,防止在小胞细胞发育过程中过度消极选择. 缺乏Fam49b会影响T细胞存活率,并减少小鼠的T细胞种群.

关键词:
家庭49bb 在线观看拉克拉克拉克拉克拉克拉克拉克在T细胞发育过程中,细胞骨重塑 细胞骨重塑免疫学 免疫学 免疫学这是一种炎症炎症炎症炎症.内皮质T细胞中的T细胞.这里是鼠标鼠标鼠标鼠标鼠标鼠标.负选择选择是负选择.

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