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Updated: Aug 1, 2026

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在分析中确定了纳米孔生成的SARS-CoV-2序列的序列污染值.

Ayooluwa J Bolaji1,2, Ana T Duggan1

  • 1Public Health Agency of Canada, National Microbiology Laboratory, Winnipeg, Canada.

PLoS computational biology
|August 19, 2024
PubMed
概括

如果污染低于特定值,从不完美的运行中获得的基因组测序数据可能是可靠的. 这一发现有助于确保准确的SARS-CoV-2血统调用,并减少浪费的测序资源.

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相关概念视频

Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...