通过外腔脊髓刺激改善横脊髓炎的次要神经缺陷:说明性的案例
Rishabh Gupta1, Reid Johnson1,2, Han Gil Jeong1
1University of Minnesota Medical School, Minneapolis, Minnesota.
Journal of neurosurgery. Case lessons
|August 19, 2024
概括
外周脊髓刺激 (eSCS) 显示出治疗横向髓炎 (TM) 的前景. 两名患有TM的患者在eSCS后经历了运动功能和膀控制的改善,这表明这种治疗在脱髓化条件下具有潜力.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 再生医学是一种再生医学.
背景情况:
- 脊髓外周刺激 (eSCS) 已用于慢性疼痛和神经缺陷.
- 有限的研究存在于eSCS对于脱髓化的疾病,如横向髓炎 (TM).
- 没有先前的病例报告详细介绍了TM患者的eSCS应用.
研究的目的:
- 调查eSCS在改善横向髓炎患者神经缺陷方面的疗效.
- 在两个TM患者中报告eSCS的结果.
主要方法:
- 两名被诊断患有横侧髓炎的患者接受了外周脊髓刺激.
- 根据运动功能,膀控制和症状变化来评估结果.
主要成果:
- 两位患者的下肢运动功能和力量均显著改善.
- 观察到改善了膀控制,包括感觉到腹和减少了 incontinence.
- 一名患者经历了腿部缩和尿路感染的减少.
- 肠道功能在两位患者中都没有显著改善.
结论:
- eSCS可能会改善横向髓炎患者的运动和膀功能.
- 这些发现支持进一步调查eSCS对脱髓化条件的研究.
- 需要更大的队列研究来证实eSCS在TM中的治疗潜力.
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