来自自然化合物的新型人类中性粒细胞弹性酶抑制剂的探索:虚拟查,体外,分子动力学模拟和体外研究研究

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Monitoring Neutrophil Elastase and Cathepsin G Activity in Human Sputum Samples
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Shanshan Zhang1, Yongguang Liu1, Suwei Jin1

  • 1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.

European journal of pharmacology
|August 19, 2024
PubMed
概括

研究人员确定了抑制人类中性粒细胞弹性酶 (HNE) 的天然化合物,这是肺损伤的关键因素. 黄类三叶在体内显示出强烈的HNE抑制和急性肺损伤 (ALI) 的减少,提供了潜在的治疗策略.

关键词:
急性肺损伤是什么?急性肺损伤是什么?这是一种HNE抑制剂.人类中性粒细胞弹性酶 (HNE)分子动力学模拟模型天然化合物是一种自然化合物.基于结构的虚拟选.

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