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Updated: Jun 16, 2025

Efficient Mammalian Cell Expression and Single-step Purification of Extracellular Glycoproteins for Crystallization
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在微质细胞表面上,TREM2与经过6O硫化和依杜龙酸修饰的肝硫酸结合并形成功能双复合体

Ilayda Ozsan McMillan1, Li Liang2, Guowei Su3

  • 1Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.

The Journal of biological chemistry
|August 19, 2024
PubMed
概括

在骨髓细胞-2 (TREM2) 上表达的触发受体将肝硫酸盐 (HS) 结合到微质上. 这种对ApoE吸收至关重要的相互作用,对于阿尔茨海默病中的微质功能至关重要.

关键词:
在TREM2中,我们可以使用TREM2.二元复杂的复杂的二进制.肝硫酸盐是什么 肝硫酸盐微质细胞中的微质细胞结构-功能的结构-功能.

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