"急性缺血性中风患者的HALP得分和感染之间的关联"
Unal Ozturk1, Sebnem Nergiz2, Onder Ozturk3
1Department of Neurology, Health Sciences University of Turkey, Diyarbakır Gazi Yasargil Education and Research Hospital, Diyarbakir, Turkey.
概括
哈尔普指数可以帮助预测急性缺血性中风 (AIS) 患者的感染风险. 较低的HALP得分与AIS病例中较高的感染率和死亡率有关,这表明其在风险评估中的有用性.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 生物化学 生物化学
背景情况:
- 与中风相关的感染 (SAI) 增加了急性缺血性中风 (AIS) 的死亡率.
- 哈尔普指数 (血红蛋白×白蛋白×淋巴细胞/血小板) 评估营养和炎症状况.
- 预测AIS患者的感染风险对于改善结果至关重要.
研究的目的:
- 研究HALP指数与AIS患者感染风险之间的关系.
- 确定HALP得分是否可以作为SAI的预测标记.
- 评估HALP得分与AIS中的死亡率之间的关联.
主要方法:
- 对132名AIS患者 (77名男性,55名女性;中位数年龄66岁) 的回顾性分析.
- 实验室变量,包括血红蛋白,白蛋白,淋巴细胞和血小板计数,在入院后24小时内进行测量.
- 使用公式计算HALP得分: (血红蛋白 × 白蛋白 × 淋巴细胞) / 血小板.
主要成果:
- 26.19.6%的AIS患者在住院后发生感染.
- 尿路感染 (50%) 和肺炎 (30%) 是最常见的感染.
- 低HALP得分 (≤18227.93) 的患者与高HALP得分 (>18227.93) (7%) 的患者相比,死亡率显著更高 (34%).
结论:
- 哈尔普指数与AIS患者的感染风险有关.
- 较低的HALP得分可能表明对感染的易感性更高,预后更差.
- 哈尔普指数显示了在AIS管理中作为预后生物标志物的潜力.
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