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Updated: Jun 16, 2025

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一种合成细胞毒性T细胞平台,用于快速原型化TCR功能

Govinda Sharma1, James Round1, Fei Teng1

  • 1Michael Smith Genome Sciences Centre, British Columbia Cancer Research Institute, Vancouver, BC, Canada.

NPJ precision oncology
|August 19, 2024
PubMed
概括

研究人员开发了一种用于T细胞受体 (TCR) 分析的新生物平台. 该系统能够快速评估TCR细胞毒性强度和抗原识别,克服当前方法的局限性.

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Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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