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Updated: Jun 16, 2025

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基于生物信息学分析,研究了NPC2基因在质瘤中的作用

Guangwei Zheng1,2, Guangming Zeng1,2, De Wei3,4

  • 1Department of Neurosurgery, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.

Scientific reports
|August 19, 2024
PubMed
概括

该NPC2基因是显著的危险因素和潜在的生物标志物质瘤,恶性脑瘤. 它的增加表达与免疫细胞活性相关,并影响患者的预后和药物敏感性.

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
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