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转基因大鼠大脑中严重的神经退行,产生人类陶

Jacob Ayers1,2, T Peter Lopez1, Ian T Steele1

  • 1Institute for Neurodegenerative Diseases, Weill Institute for Neurosciences, University of California, San Francisco, CA, 94158, USA.

Acta neuropathologica
|August 19, 2024
PubMed
概括

突变的蛋白形成子,在转基因大鼠中引起神经退行. 在接种疫苗后,半阴性老鼠发展出tau病理,模仿人类tau病变并提供对阿尔茨海默病的见解.

关键词:
过酸化过度酸化是一种马普特 (MAPT) 是一个错误折叠 没有错误折叠子是一种子.病症是一种病症.转基因的老鼠 转基因的老鼠

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