,和缺乏会损害肥胖妇女的抗氧化剂防御能力
Ana Raquel Soares de Oliveira1, Kyria Jayanne Clímaco Cruz2, Jennifer Beatriz Silva Morais3
1Postgraduate Program in Food and Nutrition, Federal University of Piauí, Teresina, Piauí, Brazil. ana.raquel@ufpi.edu.br.
概括
肥胖与,和的缺乏有关,损害了抗氧化防御. 肥胖女性的这些矿物质缺陷会对诸如超氧化脱氧化酶和谷甲氧化酶等关键酶产生负面影响.
科学领域:
- 生物化学 生化学
- 营养科学 营养科学
- 肥胖问题研究研究
背景情况:
- 肥胖与受损的内源性抗氧化剂防御系统有关.
- ,和缺乏与抗氧化能力受损有关.
研究的目的:
- 评估,和缺乏对肥胖妇女酶抗氧化剂防御的影响.
- 为了比较肥胖和肥胖妇女之间的矿物质状况和抗氧化酶活性.
主要方法:
- 一项涉及63名肥胖妇女和77名肥胖妇女的横截面研究.
- 对代谢标记,胰岛素耐药性 (HOMA-IR),β细胞功能 (HOMA-β) 和饮食摄入量进行分析.
- 测量血,红细胞和尿矿物质度,皮质醇,瘦素,氧化应激标记物和红细胞抗氧化酶活动 (SOD,GPX,催化酶).
主要成果:
- 与对照组相比,肥胖妇女的血和红细胞度较低,尿液分泌的,和较高.
- 在肥胖女性中,红细胞/度和GPX/SOD酶活性之间发现了积极的关联.
- 血清胰岛素与GPX活性呈积极关联,突出显示了的作用.
结论:
- 肥胖个体,特别是女性,在,和方面表现出缺乏.
- 这些矿物质缺乏似乎会损害抗氧化剂防御系统,导致氧化应激和肥胖的代谢障碍.
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