停止激素性别调整:一项全国性的注册研究
Riittakerttu Kaltiala1, Mika Helminen2, Timo Holttinen3
1Tampere University, Faculty of Medicine and Health Techonolgy, Tampere University Hospital and Vanha Vaasa Hospital, Tampere, 33014, Finland. Riittakerttu.kaltiala@tuni.fi.
BMC psychiatry
|August 19, 2024
概括
随着越来越多的人寻求性别调整 (GR),转变率增加. 后期的队列显示,停止荷尔蒙GR的风险更高,这表明治疗决策可能存在问题.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 越来越多的人意识到性别转换 (GR) 后的转变.
- 需要了解停药率和激素GR的风险因素.
研究的目的:
- 评估患者中断激素GR的比例.
- 确定与停止治疗相关的风险因素.
主要方法:
- 基于全国注册的后续研究.
- 统计分析包括千平方,t测试,ANOVA和考克斯回归.
- 分析了芬兰1996-2019年间接受激素GR治疗的1359名患者的数据.
主要成果:
- 7.9%的人在平均8.5年的随访期间停止了激素GR.
- 在后期的队列中 (2013-2019) 观察到更高的戒断风险.
- 在较晚的队列中,与较早的队列相比,停止治疗的危险比为2.7.
结论:
- 停止医疗GR的风险增加与患者人数的增加有关.
- 对医疗GR的潜在降低的启动值可能会导致不平衡的决策.
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