复合抗氧化剂饮食对甘油三糖指数的单一和混合关联
Yaying Xu1, Yan Zhuang2, Huifeng Zhang3
1Department of Endocrinology, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, China.
Lipids in health and disease
|August 19, 2024
概括
摄入较高的富含抗氧化剂的食物,特别是维生素E,与通过甘油三-葡萄糖指数 (TyG) 测量的较低的胰岛素抵抗 (IR) 有关. 这表明补充维生素E可能会改善IR,尽管超重或糖尿病患者的益处可能会减少.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 氧化应激与胰岛素抵抗 (IR) 有关.
- 饮食中抗氧化剂摄入量与IR,特别是甘油三-葡萄糖指数 (TyG) 之间的关联仍然不清楚.
- 综合饮食抗氧化剂指数 (CDAI) 和其成分与TyG的关系需要进一步调查.
研究的目的:
- 调查CDAI及其组成部分与TyG之间的关联.
- 探索饮食中抗氧化剂在调节胰岛素抵抗中的作用.
- 为了确定可能影响TyG指数的特定营养素.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2003-2018) 的横截面分析.
- 使用多变量线性回归,加权量子素和回归 (WQS) 和贝叶斯内核机器回归 (BKMR).
- 进行了子组和灵敏度分析以证实发现.
主要成果:
- 在14673名参与者中,CDAI和TyG之间发现了显著的负相关性.
- 维生素E成为最有影响力的抗氧化成分,与TyG负面相关.
- 在超重/肥胖和糖尿病小组中,相关性较弱.
结论:
- 富含抗氧化剂的饮食,特别是富含维生素E的饮食,与改善胰岛素敏感性有关.
- 补充维生素E可能是管理胰岛素抵抗的一个有价值的策略.
- 患有肥胖或糖尿病的人可能会体验到抗氧化剂饮食的益处减少,这需要进一步的研究.
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