地中海盆地的猫类莱什曼病:一个多中心研究
Mariaelisa Carbonara1, Roberta Iatta2, Guadalupe Miró3
1Department of Veterinary Medicine, University of Bari, Bari, Italy.
Parasites & vectors
|August 19, 2024
概括
猫类莱什曼病 (FeL) 影响地中海盆地的家养猫,其中17.3%的猫检测结果为Leishmania infantum阳性. 风险因素包括住房和FIV感染,FeL与特定的临床症状和血液异常有关.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 流行病学 流行病学
- 猫类传染病 猫类传染病
背景情况:
- 猫是Leishmania infantum的合格宿主,作为沙传播的储存库.
- 关于地中海盆地猫类莱什曼病 (FeL) 的大规模流行病学数据有限.
- 本研究涉及6个地中海国家的FeL的流行率,危险因素和临床表现.
研究的目的:
- 为了确定Leishmania婴儿感染在家猫中的流行率.
- 为了确定与FeL相关的风险因素.
- 记录感染猫的临床症状和临床病理异常.
主要方法:
- 一项涉及意大利,希腊,葡萄牙,法国,以色列和西班牙2067只猫 (2019-2022) 的横截面研究.
- 对L.infantum进行血清学测试 (IFAT,ELISA),在阳性病例中检测DNA.
- 收集有关动物人口统计,住房,临床症状和临床病理参数的数据,包括FIV和FeLV的同时感染.
主要成果:
- 婴儿菌的总体血清流行率为17.3%,因国家而有显著差异.
- 住房条件和患有猫免疫缺陷病毒 (FIV) 的同时感染被确定为FeL的风险因素.
- 血清阳性与体重减轻,淋巴腺巨变,口腔病变以及特定的血液和生化变化相关.
结论:
- 在地中海盆地内,Leishmania infantum 在家猫中很普遍.
- 庇护所/自由流浪的猫和与FIV同时感染的猫特别面临风险.
- 这项研究为FeL及其临床影响提供了关键的流行病学见解.
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