韩国儿童炎症性肠病流行病学按年龄子组分类
Yeong Eun Kim1, Seo-Hee Kim2, Seong Pyo Kim3,4
1Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Republic of Korea.
概括
儿童炎症性肠病 (PIBD) 发病率在全球范围内不断上升,韩国数据显示,在年龄较大的儿童 (6-16岁) 中显著增加,但在婴儿中没有. 在老年人群中注意到克罗恩病的区域变异.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 儿科 儿科 儿科
背景情况:
- 儿童炎症性肠病 (PIBD) 的发病率在全球范围内不断上升.
- 亚洲人群中特定年龄的PIBD流行病学的研究是有限的.
- 本研究检查了韩国不同年龄小组的PIBD流行病学.
研究的目的:
- 调查韩国PIBD的发生率和趋势.
- 分析PIBD中特定年龄的流行病学差异.
- 探索 PIBD 发病率的区域差异.
主要方法:
- 从2005年到2016年,利用了全国范围的韩国卫生管理数据.
- 将患者分为四个年龄组:0-1,2-5,6-9岁和10-16岁.
- 采用波桑回归分析来评估发病率,时间变化和区域差异.
主要成果:
- 总体而言,GDPD的发病率从1.173/10^5 PY (2005-2007) 增加到3.267/10^5 PY (2014-2016). 在过去的几年里,GDPD的发病率从1.173/10^5 PY (2005-2007) 增加到3.267/10^5 PY (2014-2016).
- 在0-5岁年龄组,发病率保持稳定,但在6-16岁年龄组显著增加.
- 克罗恩氏病的发病率在老年儿童 (6-16岁) 中呈现区域差异,与性结肠炎不同.
结论:
- 时间趋势和GDPB的区域差异因年龄分组而异.
- 表明遗传和环境因素对儿科年龄组内IBD发育的不同影响.
- 强调需要针对 PIBD 进行特定年龄的研究和干预措施.
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