在食道癌患者中进行术后肺炎的风险预测模型:系统性审查
Yaxin Jiang1,2, Zimeng Li2, Weiting Jiang1
1Department of Healthcare-Associated Infection Management, The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
这项研究发现,虽然食道癌手术中术后肺炎的风险预测模型显示出良好的歧视性,但所有模型都有高偏差风险. 未来的研究需要更大的样本和外部验证来改进模型设计.
科学领域:
- 医疗信息学 医疗信息学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 手术后肺炎 (POP) 对接受食道癌 (EC) 手术的患者来说是一个显著的风险.
- 现有的EC患者中POP风险预测模型需要质量和适用性评估.
- 这项研究系统地评估了这些模型的偏差和适用性.
研究的目的:
- 在食道癌患者中系统评估术后肺炎现有风险预测模型的偏差风险和适用性.
- 确定共同的预测因素,并评估这些模型的性能.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science等) 进行了全面的文献搜索. 在2024年3月之前.
- 两名独立调查人员对研究进行了选,并提取了数据.
- 预测模型偏差风险评估工具 (PROBAST) 用于评估偏差风险和适用性.
主要成果:
- 包含了23个模型的14项研究,主要在2014-2023年之间发表.
- 所有模型都表现出良好的适用性,但由于数据来源,样本大小,可变处理和缺乏验证,存在高偏差风险.
- 常见的预测因素包括吸烟,年龄,COPD,糖尿病和胸切除术;模型歧视范围从0.627到0.850.
结论:
- 在EC手术中对POP的风险预测模型显示出良好的歧视,但存在高偏差风险.
- 研究设计的改进,更大的样本大小和多中心外部验证对于开发可靠模型至关重要.
- 这些发现强调了需要严格的评估工具,如PROBAST,以加强未来的模型开发.
更多相关视频
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
04:32Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
相关概念视频
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
Pneumonia III: Complications and Assessment
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Cancer Survival Analysis
