在解除COVID-19限制后,中风后抑郁症的危险因素
Shangyu Luo1, Xueqin Hu2, Yunjun Hong1
1Department of Neurology, Changde Hospital, Xiangya School of Medicine, Central South University (The First People's Hospital of Changde City), Changde City, Hunan Province, People's Republic of China.
International journal of general medicine
|August 20, 2024
概括
在COVID-19限制放松后,中风后抑郁症 (PSD) 影响了14.15%的患者. 关键的危险因素包括C反应蛋白 (CRP),家族中风病史,偏头痛,睡眠时间和甲状腺刺激激素 (TSH).
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 脑卒中后抑郁症 (PSD) 是中风后的一个常见并发症.
- 在放松COVID-19限制后,PSD流行率和风险因素的研究有限.
- 了解这些因素对于及时干预和改善患者结果至关重要.
研究的目的:
- 调查COVID-19限制解除后中风患者中PSD的流行情况.
- 在这个人群中确定与PSD相关的因素.
- 为临床实践和未来研究方向提供信息.
主要方法:
- 一项涉及947名中风患者 (脑出血和心脏病发作) 的横截面研究.
- 收集的数据包括人口统计信息,用于抑郁症查的患者健康问卷-9 (PHQ-9),C反应蛋白 (CRP),同类氨酸 (Hcy),修改的兰金尺度 (mRS),中风特征和甲状腺刺激激素 (TSH).
- 用多重回归分析来确定PSD的独立风险因素.
主要成果:
- 后视障碍的患病率为14.15% (PHQ-9分数≥5).
- 以前的COVID-19感染与PSD没有显著的相关性.
- 独立的PSD风险因素包括CRP水平升高,家族中风史,偏头痛史,睡眠时间缩短和TSH水平.
结论:
- 脊髓炎,家族中风病史,偏头痛,睡眠时间和TSH是PSD的重要独立风险因素.
- 这些发现强调了在流行病后对中风患者的管理中考虑这些因素的重要性.
- 需要进一步的研究来探索潜在的机制,并为PSD制定有针对性的干预措施.
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