使用便样本的多重聚合酶链反应面板增强了细胞巨病毒结肠炎的临床诊断:一个病例报告
Shinobu Hosokawa1, Akihiro Bessho1, Mai Kagawa2
1Department of Respiratory Medicine, Japanese Red Cross Okayama Hospital, Okayama, JPN.
Cureus
|August 20, 2024
概括
在免疫功能低下的患者中,细胞巨病毒 (CMV) 大肠炎的诊断具有挑战性. 当结肠镜检查是不可行的时,便的多重PCR成功检测到CMV,从而能够及时治疗甘西克洛维尔.
科学领域:
- 传染性疾病 传染性疾病
- 胃肠病学 胃肠病学
- 分子诊断学 分子诊断
背景情况:
- 一名患有肺癌的71岁男性在手术后经历了急性呼吸衰竭,需要机械通风和免疫抑制治疗.
- 患者出现严重的水性腹,促使对肠道感染进行调查.
- 标准便培养和多重PCR检测胃肠道病原体是负的.
相关概念视频
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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Cytomegalovirus Disease
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...


