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Updated: Jun 16, 2025

Assessment of Selective mRNA Translation in Mammalian Cells by Polysome Profiling
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在c-myc翻译期间的核糖体停滞,呈现出可操作的癌细胞脆弱性

Tejinder Pal Khaket1, Suman Rimal1, Xingjun Wang1

  • 1Department of Pathology and Programs in Neuroscience and Cancer Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

PNAS nexus
|August 20, 2024
PubMed
概括

核糖体质量控制 (RQC) 维持了Myc蛋白水平. 针对c-Myc翻译中的核糖体停滞,揭示了癌细胞的脆弱性,提供了新的治疗策略.

关键词:
在 Nsp1 中使用.cMycMyc是什么意思癌症 癌症 癌症 癌症 癌症核糖体相关质量控制 (RQC)翻译停滞不前 翻译停滞不前

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