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Updated: Jun 16, 2025

Generation of Induced-pluripotent Stem Cells Using Fibroblast-like Synoviocytes Isolated from Joints of Rheumatoid Arthritis Patients
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细胞特异性基因网络和驱动器在类风湿性关节炎的突组织

Aurelien Pelissier1,2,3, Teresina Laragione4, Percio S Gulko4

  • 1Institute of Computational Life Sciences, Zürich University of Applied Sciences (ZHAW), Wädenswil, Switzerland.

Frontiers in immunology
|August 20, 2024
PubMed
概括

这项研究揭示了关键的转录因子 (TFs) 驱动类风湿性关节炎 (RA) 在突组织. 在纤维细胞样同胞细胞,T细胞,B细胞和单细胞中识别这些调节剂为RA提供了新的治疗点.

关键词:
在FLS中,使用FLS.一个T细胞细胞.共同监管是一种共同监管.基因调控网络 (GRN) 是一种基因调控网络.关键驱动器驱动器关键驱动器一个单细胞单细胞.类风湿性关节炎 类风湿性关节炎转录组因子是一个转录组因子.

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