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带状带异常与急性初级角关闭交织在一起:一个诊断和治疗的挑战
Hong Chen1, Juan Yin1, Yixiang Wu2
1Department of Glaucoma, Hebei Eye Hospital, Hebei Key Laboratory of Ophthalmology, Hebei Provincial Clinical Research Center for Eye Diseases, 054001, Xingtai, Hebei, China.
Heliyon
|August 20, 2024
概括
浅的前腔深度 (ACD) 和较大的眼睛之间的ACD差异 (ACDD) 是急性初级角度闭合 (APAC) 中透镜带状异常的关键指标. 皮洛卡在这些患者中有效地控制眼内压力.
科学领域:
- 眼科医生 眼科 眼科
- 解剖学和临床研究.
- 外科手术的结果
背景情况:
- 急性初级角关闭 (APAC) 是一种危急的眼科疾病.
- 镜片带状带异常可能使亚太地区的管理复杂化.
- 了解风险因素和治疗疗效对于患者的治疗结果至关重要.
研究的目的:
- 在亚太地区调查与透镜带状带异常相关的患者特征.
- 确定导致这些异常的风险因素.
- 为了评估Pilocarpine作为APAC患者的肌肉激活剂的疗效.
主要方法:
- 在河北省眼科医院 (2019-2021) 进行了回顾性病例对照研究.
- 对亚太地区患者中带状带状况的手术内指标的分析.
- 亚太地区和亚太地区与透镜外置 (APACLS) 组之间的人口和眼部生物识别数据 (ACD,AL,ACDD,LT,LP,RLP) 的比较.
- 评估Pilocarpine对眼内压力 (IOP) 的影响以及包括ROC曲线在内的统计分析.
主要成果:
- 在APAC和APACLS组之间,年龄或轴长没有显著差异.
- APACLS组表现出更大的镜片厚度 (LT),较浅的前腔深度 (ACD),较大的眼睛之间的ACD差异 (ACDD) 和较低的镜片位置 (LP/RLP).
- 浅ACD (<1.6毫米) 和大ACDD (>0.375毫米) 被确定为区域性异常的重要危险因素.
- 皮洛卡在75.36%的APAC患者和71.43%的APACLS患者中使IOP正常化.
结论:
- 在亚太地区,浅浅的ACD和大的ACDD表明透镜外置的风险增加.
- 在ACD<1.6mm和ACDD>0.375mm的情况下,需要考虑带状带异常.
- 皮洛卡证明了作为亚太地区有区域性异常的APAC患者的肌肉治疗的安全性和有效性.
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