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新型诊断方法和冠状动脉微血管功能障碍的管理

Graziella Pompei^1,2, Nandine Ganzorig¹, Christos P Kotanidis^1,3

¹Translational and Clinical Research Institute, Faculty of Medical Sciences, NewcastleUniversity, Newcastle upon Tyne, UK.

American journal of preventive cardiology

|August 20, 2024

概括

冠状动脉非阻塞性缺血 (INOCA) 是常见的,并与微血管功能障碍有关. 研究正在完善INOCA的诊断和治疗,改善患者的治疗结果并降低医疗保健成本.

科学领域:

心脏病学心脏病学
心血管研究研究心血管研究
医学诊断医学诊断医学诊断

背景情况:

缺血性心脏病 (IHD) 通常与阻塞性冠状动脉疾病 (CAD) 相关.
超过50%的接受血管造影的患者有非阻塞性冠状动脉,这引起了人们对非阻塞性冠状动脉 (ANOCA/INOCA) 的心痛/缺血的兴趣.
INOCA涵盖冠状动脉血管疾病,包括冠状动脉微血管功能障碍 (CMD) 和血管痛,这些疾病可以与阻塞性CAD共存.

研究的目的:

审查冠状动脉微血管功能障碍 (CMD) 的诊断方法.
概述INOCA患者治疗管理的顺序.
总结有关诊断和管理INOCA的当前数据.

主要方法:

对当前数据进行叙述性审查.
讨论诊断模式,包括非侵入性成像,侵入性冠状动脉血管功能测试和血管学衍生指数.
专注于CMD的表征.

主要成果:

冠状动脉微血管功能障碍 (CMD) 是INOCA的一个关键机制,在患有慢性冠状动脉综合征的女性中尤其普遍.
在INOCA中,冠状动脉流量储备受损与主要不良心血管事件增加有关.
INOCA患者报告生活质量下降和医疗保健成本上升.

结论:

脑膜炎症是一种严重的疾病,需要更好的定义,分类和预后分层.
通过先进的成像和功能测试,可以实现CMD的全面表征.
结构化的诊断和治疗方法对于管理INOCA和CMD至关重要.

关键词:

冠状动脉的流量储备.冠状动脉微血管功能障碍冠状动脉微血管功能障碍微血管抵抗性的指数缺血与非阻塞性冠状动脉.微血管性心痛是什么意思

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