心脏的可塑性是对身体活动变化的反应
Eric T Hedge1,2, Tiffany L Brazile3,4, Richard L Hughson1
1Schlegel-UW Research Institute for Aging, Waterloo, Canada.
The Journal of physiology
|August 20, 2024
概括
身体活动显著影响心脏健康. 不活动会导致心脏缩,而耐力训练会增强心脏功能,作为对策. 终身炼可以随着年龄的增长保持心脏可塑性.
科学领域:
- 心血管生理学心血管生理学
- 运动科学 运动科学
- 衰老研究研究 衰老研究
背景情况:
- 人类的心脏在应对身体活动水平时表现出了显著的适应能力.
- 心脏结构和功能因不活动 (床上休息,太空飞行) 和运动训练而显著改变.
- 衰老代表了长期不活动的模式,影响心脏可塑性.
研究的目的:
- 总结心脏适应不同体力活动水平的情况,包括不活动和运动.
- 要突出衰老对心脏可塑性的影响.
- 识别有关心脏重塑和不同刺激和衰老下的功能方面的知识差距.
主要方法:
- 关于心脏适应的现有文献的审查和综合.
- 对涉及床上休息,太空飞行和耐力运动训练的研究进行分析.
- 检查衰老和心脏可塑性之间的相互作用,以应对身体活动变化.
主要成果:
- 严重的不活动 (床上休息,太空飞行) 会导致心脏缩和心室血管硬.
- 耐力训练促进了奇特的缩,增强了心室合规性,并抵消了不活动引起的变化.
- 久坐式衰老导致同心重塑和不可逆转的硬化;终身运动可以防止与年龄相关的变化并保持合规性.
结论:
- 心脏可塑性受到身体活动的影响,不活动是有害的,耐力运动是有益的.
- 虽然炼可以缓解一些与年龄相关的心脏硬化,但老年人开始在生命的后期训练时,可塑性会降低.
- 需要进一步的研究,以了解影响心脏对训练/脱条件和长期太空飞行效应反应的因素.
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