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系统性审查中的异质结果选择和不完整的结果预规范:压力损伤的案例研究

Jun Zhang¹, Mingyue Zhang, Caihua Xu

¹At the Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China, Jun Zhang, MD, is Lecturer; Mingyue Zhang, BS, and Caihua Xu, BS, are Master's Students; Jinhui Tian, PhD, is Professor; and Donghua Yang, MD, is Lecturer. Bo Wang, MD, is Associate Professor, School of Nursing, Gausu University of Chinese Medicine, Lanzhou.

Advances in skin & wound care

|August 20, 2024

概括

对压力损伤 (PI) 干预措施的系统性审查使用了各种结果,预先规格不佳. 需要一个核心结果集来标准化压力损伤的关键临床结果.

科学领域:

医学研究方法论医学研究方法论.
基于证据的实践实践.
临床试验的设计

背景情况:

系统性审查 (SRs) 对于综合压力损伤 (PI) 干预措施的证据至关重要.
了解SR中结果是如何选择和预规定的,对于评估其质量和适用性至关重要.
之前的审查强调了结果报告的变化,但缺乏对预规格完整性的详细分析.

研究的目的:

调查PI干预和治疗的SR报告中报告的结果.
评估这些SR中结果预规范的完整性.
确定在IP研究中需要标准化结果报告的需要.

主要方法:

在四个电子数据库中进行了系统的搜索,搜索PI预防和/或治疗的SR.
纳入标准侧重于SR和元分析,包括系统搜索和偏见风险评估.
两位审查员提取了结果数据,将其分类为领域,并使用五要素框架评估了预规格.

主要成果:

包括95个SR,报告了24个结果域中的432个实例,平均每个SR有4个域.
最常见的结果是PI愈合,PI发生和PI状态.
只有5.56%的报告结果是完全规定的,而64.52%的SR预先规定的主要结果列出了超过一个.

结论:

针对PI干预措施的SR报告了多样化和不完全预先规定的结果.
需要一个标准化的核心结果集,以确保压力损伤关键临床结果报告的一致性.
改进结果预规范将提高SRs在指导临床实践和未来研究中的可比性和实用性.

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