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将广谱β-乳酸盐与氨基糖化物相结合的活性与产生VIM的Enterobacteriaceae进行比较

Justin A Clark1, David S Burgess1

  • 1College of Pharmacy, University of Kentucky, Lexington, Kentucky, USA.

Microbiology spectrum
|August 20, 2024
PubMed
概括

产生金属β-乳糖酶 (MBL) 的抗卡巴因耐药肠道细菌 (CRE) 需要联合抗生素治疗. 梅罗尼姆加上氨基糖化物和阿兹特雷诺姆/阿维巴克坦显示出对VIM-CRE的快速杀菌活性.

关键词:
它们是Enterobacteriaceae的细菌.维罗纳整体子编码的金属β-乳糖酶.氨基甘油酸氨基化物.对抗微生物的敏感性.贝塔乳糖类药物 贝塔乳糖类药物碳烯的耐药性 碳烯的耐药性时间杀手的时间杀手

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