在临床实践中的Helicobacter pylori诊断中的特征性内镜发现
Mitsushige Sugimoto1, Masaki Murata2, Kazunari Murakami3
1Division of Genome-Wide Infectious Diseases, Research Center for GLOBAL and LOCAL Infectious Disease, Oita University, Yufu, Japan.
Expert review of gastroenterology & hepatology
|August 20, 2024
概括
本综述详细介绍了当前Helicobacter pylori (H. pylori) 感染的内镜检测结果. 精确的内镜评估有助于胃癌查和风险分层.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 在瘤学瘤学.
背景情况:
- 杆菌感染是胃癌的主要危险因素.
- 胃癌的死亡率可以通过早期检测通过使用高视野内镜的查程序来减少.
- 在日本使用的京都胃炎分类,依赖于风险分层的内镜评估.
研究的目的:
- 描述当前H. pylori感染的内镜特征.
- 解释如何评估特征性内镜检测结果.
- 通过敏感的检测方法强调H. pylori诊断的重要性.
主要方法:
- 对与H. pylori感染相关的内镜检测结果的审查.
- 胃炎的分类为H.pylori阴性,不活跃的胃炎 (以前的感染) 和活跃的胃炎 (当前的感染).
- 鉴定活性胃炎和与H. pylori相关的胃炎的主要内镜特征.
主要成果:
- 活跃的H. pylori胃炎显示了诸如分散的红色,扩大的,结节,粘膜胀和粘性粘液等发现.
- 与H. pylori相关的胃炎 (活跃或不活跃) 呈现为缩,肠道转化和仙瘤.
- 精确的内镜评估至关重要,但确切的诊断需要敏感的测试,如便抗原或尿素呼吸测试.
结论:
- 京都分类为H. pylori胃炎的内镜风险评估提供了一个框架.
- 内镜检测对于识别潜在的H. pylori感染至关重要.
- 应使用高度敏感和特定的诊断测试来确认H. pylori感染.
相关概念视频
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
101
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
101
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
335
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
335
Gastritis III: Clinical Manifestations and Management
192
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
192
Peptic Ulcer Disease I: Introduction
161
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
161
Endoscopic Procedures I: Esophagogastroduodenoscopy
79
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
79
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
546
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
546


