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自动伤口关闭系统:通过拉伸伤口周围的皮肤来关闭大伤口

Jin Jian^1,2, Chen Ji-Qiu³, Chen Zheng-Li³

¹State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, People's Republic of China.

Updates in surgery

|August 20, 2024

概括

一个自动伤口关闭系统安全地拉伸皮肤以覆盖大伤口,实现初级关闭并减少痕. 这种创新的装置为传统的移植方法提供了替代方案.

科学领域:

生物医学工程生物医学工程
伤口治愈研究研究伤口治愈研究
再生医学是一种再生医学.

背景情况:

较大的伤口往往需要皮肤移植或片移植,从而导致二次伤害.
目前的治疗方法可能会导致显著的痕和长时间的恢复.
需要先进的伤口关闭技术来最大限度地减少阳性损伤.

研究的目的:

开发和评估用于大伤口的自动伤口关闭系统.
为了比较自动系统与猪手动接的有效性.
评估不同引力对伤口愈合和痕形成的影响.

主要方法:

设计了一个自动伤口关闭系统,配有伸缩模块,微控制器和触摸屏.
巴马小型猪的全厚伤口用手工或自动装置在15N,30N或60N处进行治疗.
评估了伤口关闭,愈合,痕质量,原纤维变化,亡和血管密度.

主要成果:

只有在30N和60N的引力下,自动系统才能实现初级伤口关闭.
发生了原纤维的拉伸,在60N时分解.
痕增生症在自动系统的使用下显著减少.
早期关闭后的原蛋白,亡和血管性的变化随着时间的推移而正常化.

结论:

自动伤口关闭系统有效地实现了使用适当的引力 (30N) 进行大伤口的初级关闭.
与手工接相比,这种方法可以减少痕增生.
该系统安全地拉伸皮肤和皮肤原蛋白,为移植提供了一个有希望的替代方案.

关键词:

自动伤口关闭系统自动伤口关闭系统原蛋白是一种原蛋白蛋白.伤口伤口伤口伤口伤口伤口愈合伤口愈合

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