治疗期间与化疗有关的不良症状的有氧训练的有效性:随机对照试验与成本效益评估的随机对照试验协议
William de Lima Selles1, Gisela Cristiane Miyamoto1, Elinaldo da Conceição Santos2
1Master's and Doctorate Program, Universidade Cidade de São Paulo, Sao Paulo, Brazil.
JMIR research protocols
|August 20, 2024
概括
这项研究调查了接受化疗的住院癌症患者的有氧运动. 运动可以减少化疗副作用,改善患者的生活质量,并可能扩大物理治疗师在瘤学中的角色.
科学领域:
- 在瘤学瘤学.
- 运动生理学 运动生理学
- 临床试验 临床试验
背景情况:
- 化疗往往会产生不良影响,影响癌症患者的生活质量.
- 目前化学疗法患者的运动干预措施在类型,强度和时间上缺乏共识.
- 大多数研究集中在乳腺癌门诊患者身上,与本次试验的住院,多样化的癌症患者群体不同.
研究的目的:
- 评估有氧训练对化疗相关症状 (恶心,吐,喘息,虚弱),疲劳,移动性和住院治疗的影响.
- 评估患者的满意度,有氧训练的不良影响和干预的成本效益.
- 探索物理治疗师在瘤学中的角色的潜在扩展.
主要方法:
- 一项随机对照试验,盲目的评估,包括94名住院癌症患者.
- 干预组:在化疗期间进行有氧训练;对照组:保持活力的小册子.
- 使用线性混合模型,卡普兰-梅尔分析,奇平方测试和生活质量评估 (EQ-5D-3L) 测量结果.
主要成果:
- 临床试验注册获得批准2023年3月.
- 招聘和数据收集正在进行中.
- 研究结果预计将在2025年底发表.
结论:
- 有氧运动提供了一种简单,廉价的方法来减轻化疗副作用.
- 积极的发现可以支持将运动干预措施纳入标准癌症护理.
- 这项研究可能会扩大瘤学环境中的物理治疗师的实践范围.
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