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Updated: Jun 16, 2025

Transient Expression of Proteins by Hydrodynamic Gene Delivery in Mice
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Published on: May 5, 2014

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在APOL3中蛋白质截断变异增加了APOL1风险等位基因的长期病风险

David Y Zhang1,2, Michael G Levin3,4, Jeffrey T Duda5

  • 1Department of Genetics.

JCI insight
|August 20, 2024
PubMed
概括

一种新的APOL3基因变异 (p.Q58*) 显著增加慢性病 (CKD) 风险,特别是在具有APOL1风险变异的个体中. 这一发现突显了病中人口特异性遗传因素的重要性.

关键词:
慢性脏疾病 慢性脏疾病遗传变异是一种遗传变异.遗传学 是一个遗传学.腎臟病學 (nephrology) 是一種醫學專業.

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