Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

DNA as a Genetic Template02:05

DNA as a Genetic Template

6.8K
6.8K
DNA Base Pairing02:27

DNA Base Pairing

27.2K
Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
27.2K
DNA Topoisomerases02:02

DNA Topoisomerases

31.1K
Topoisomerases are enzymes that relax overwound DNA molecules during various cell processes, including DNA replication and transcription. These enzymes regulate positive and negative DNA supercoiling without changing the nucleotide sequence. DNA overwinding in a clockwise direction results in positively supercoiled DNA, whereas underwinding in a counterclockwise direction produces negatively supercoiled DNA.
Types and Mechanism of action
Topoisomerases are divided into two main types. ...
31.1K
The DNA Replication Fork01:02

The DNA Replication Fork

15.3K
15.3K
The DNA Helix01:16

The DNA Helix

138.8K
Overview
138.8K
DNA Replication02:40

DNA Replication

49.0K
DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
49.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Macrophages de<i>liver</i> growth.

Science signaling·2025
Same author

Making sense of gastric cancer.

Science signaling·2025
Same author

Alarmin' lymphoid developments.

Science signaling·2025
Same author

In Science Journals.

Science (New York, N.Y.)·2025
Same author

Healing limited.

Science signaling·2024
Same author

Neurons go antiviral.

Science signaling·2024

相关实验视频

Updated: Jun 16, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

4.2K

一个DNA的中风.

Amy E Baek1

  • 1Science Signaling, AAAS, Washington, DC 20005, USA.

Science signaling
|August 20, 2024
PubMed
概括

循环的无细胞DNA激活了炎症体,这是一个关键的免疫通路. 这种激活与动脉样硬化患者的复发性中风有关.

科学领域:

  • 免疫学 免疫学 免疫学
  • 神经学 神经学
  • 心血管科学 心血管科学

背景情况:

  • 动脉样硬化是复发性中风的主要危险因素.
  • 炎症酶激活在炎症性疾病中起作用.
  • 循环DNA在中风病原性中的作用尚未完全理解.

研究的目的:

  • 在动脉样硬化患者中调查循环DNA,炎症酶激活和复发性中风之间的联系.

主要方法:

  • 在患者中评估循环无细胞DNA (cfDNA) 的水平.
  • 测量了炎性酶激活标志物.
  • 与中风复发相关的cfDNA水平和炎症酶活性.

主要成果:

  • 在患有复发性中风的患者中发现了高cfDNA水平.
  • 较高的炎症酶激活与增加的cfDNA相关.
  • cfDNA驱动的炎症酶激活与复发性中风的风险更高有关.

结论:

  • 循环DNA是炎症酶激活的潜在驱动因素.
  • 这一途径有助于在动脉样硬化中重复性中风.

更多相关视频

Studying DNA Looping by Single-Molecule FRET
11:27

Studying DNA Looping by Single-Molecule FRET

Published on: June 28, 2014

15.4K
A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
12:05

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA

Published on: October 1, 2017

8.1K

相关实验视频

Last Updated: Jun 16, 2025

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
09:26

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation

Published on: December 29, 2021

4.2K
Studying DNA Looping by Single-Molecule FRET
11:27

Studying DNA Looping by Single-Molecule FRET

Published on: June 28, 2014

15.4K
A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA
12:05

A Simple, Robust, and High Throughput Single Molecule Flow Stretching Assay Implementation for Studying Transport of Molecules Along DNA

Published on: October 1, 2017

8.1K
  • 针对cfDNA或炎症酶可以提供新的治疗策略.