微量饮食多醇摄入量与健康成年人的全身和胃肠道炎症有关
Stephanie Mg Wilson1, Andrew Oliver2, Jules A Larke2
1United States Department of Food and Agriculture, Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, United States; Texas A&M AgriLife Research, Institute for Advancing Health Through Agriculture, College Station, TX, United States.
饮食中的多,在茶,咖啡和水果中丰富,显示出抗炎作用. 在健康的成年人中,更高的摄入量与胃肠道炎症标志物减少有关.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 免疫学 免疫学 免疫学
背景情况:
- 饮食中的多是具有已知的抗炎性质的生物活性化合物.
- 有限的数据存在于类/化合物水平的多摄入量及其与炎症的联系.
研究的目的:
- 在健康的成年人中量化饮食中的多醇摄入量.
- 研究聚醇摄入量与胃肠道 (GI) 和全身炎症标志物之间的关联.
主要方法:
- 这是一项对350名健康成年人的观察性,横截面研究.
- 通过24小时回忆评估的饮食摄入量,映射到FooDB以估计多 (总数,类,化合物).
- 统计分析包括线性模型和随机森林回归.
主要成果:
- 平均总聚醇摄入量为~914 mg/1000 kcal/d;黄类是主要类.
- 较高的聚醇总摄入量与较低的便calprotectin (GI炎症标志物) 有关.
- 特定的多类 (prenol脂类, phenylpropanoic酸) 与降低的GI透性标记物相关.
结论:
- 饮食中摄入的多烯与健康成年人胃肠道炎症的减少有关.
- 特定的多类,如先脂和烯酸,可能会降低GI透性.
- 聚醇对炎症的影响是复杂的,取决于摄入的分辨率 (总量,类,化合物).
更多相关视频
08:58Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
Published on: January 5, 2017
12:00Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
Published on: July 5, 2017
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Assessment of the Gastrointestinal System II: Health Perception Pattern
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Assessment of the Gastrointestinal System I: Subjective Data
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
