饮食摄入量与发生慢性病之间的关联:一个前性观察队列研究
Hee Byung Koh1, Hyo Jeong Kim2, Ga Young Heo3
1Department of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, Republic of Korea; Catholic Kwandong University International Saint Mary's Hospital, Seo-gu, Incheon, South Korea.
The American journal of clinical nutrition
|August 20, 2024
概括
饮食中较低的摄入量与成人患慢性病 (CKD) 的风险增加有关. 确保足够的摄入量可能对脏健康至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 血清缺乏与心血管疾病风险增加有关.
- 饮食摄入量与慢性病 (CKD) 风险之间的关系尚未得到充分证实.
研究的目的:
- 研究饮食摄入量与正常功能成年人中慢性病发病率之间的关联.
主要方法:
- 一项对188,510名英国生物库参与者的前性观察队列研究.
- 饮食摄入量通过24小时回忆评估并分为五分之一.
- 在一个子队列中,使用ICD-10代码和eGFR<60mL/min/1.73m2识别的事件CKD.
主要成果:
- 较低的摄入量与较高的CKD发病率相关.
- 发生性CKD的危险比率随着摄入量五分位数的下降而逐步增加 (Q1与Q5:调整HR 1.30 [1.201.41]).
- 对于eGFR定义的CKD结果观察到类似的关联.
结论:
- 减少饮食摄入量与正常功能成年人患CKD的风险增加有关.
- 需要进一步的研究,包括对照性研究,以确认足够的摄入量对脏健康的保护作用.
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