通过使用深度神经网络在多读器数据集上的胸部X射线对肺部疾病的信心意识严重性评估
Mohammadreza Zandehshahvar1, Marly van Assen2, Eun Kim2
1School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, USA.
Journal of imaging informatics in medicine
|August 20, 2024
概括
使用贝叶斯神经网络 (BNNs) 的新方法接近蒙特卡洛脱落 (MCD) 来准确地从胸部X射线 (CXRs) 进行COVID-19肺部疾病严重程度分类,超过人类放射学家.
科学领域:
- 人工智能的人工智能
- 医疗成像医学成像
- 放射学 放射学是一门学科.
背景情况:
- 使用胸部X射线 (CXRs) 对COVID-19患者肺部疾病的确切严重程度分类对于患者管理至关重要.
- 现有的方法可能缺乏可信度指标,限制了它们的临床实用性.
- 贝叶斯神经网络 (BNNs) 提供了一种概率方法来增强诊断模型.
研究的目的:
- 开发和评估使用CXRs的COVID-19肺部疾病的信心意识严重程度分类模型.
- 为了近似贝叶斯神经网络 (BNNs) 使用蒙特卡罗脱落 (MCD) 为此任务.
- 评估模型与人类读者的性能及其概括能力.
主要方法:
- 基于蒙特卡洛脱落 (MCD) 的方法被用作贝叶斯神经网络 (BNN) 的近似.
- 该模型在1208个CXR上进行了训练和测试,将严重程度分为正常,轻度,中度和严重的类别.
- 在各种数据集 (2200 和 1300 CXR) 上进行了内部验证和外部测试.
主要成果:
- 该模型在初级数据集上实现了0.94 ± 0.01的曲线下的平均面积 (AUC).
- 它在每个严重程度类别中都超过了人类读者,肯德尔相关系数 (KCC) 为0.80±0.03.
- 在各种数据集中一致的性能显示出强大的概括能力.
结论:
- 开发的BNN模型有效地将COVID-19肺部疾病严重程度从CXRs分类,优于人类读者.
- 预测不确定性 (PU) 测量与放射科医生的同意相关,有助于临床决策.
- 该模型的信心意识预测提高了诊断精度,并显示了临床应用的潜力.
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