德国呼吸道同胞病毒 (RSV) 感染的负担:系统性审查
Anahita Poshtiban1, Moritz Wick2, Mathieu Bangert3
1Sanofi-Aventis Deutschland GmbH, Lützowstr. 107, 10785, Berlin, Germany. anahita.poshtiban@sanofi.com.
BMC infectious diseases
|August 20, 2024
概括
呼吸道同胞病毒 (RSV) 在德国显著影响婴儿,幼儿和老年人. 需要对健康儿童和老年人进行进一步的研究,以了解RSV的全部医疗和经济负担.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 卫生经济学 卫生经济学
背景情况:
- 呼吸道同胞性病毒 (RSV) 是脆弱人群中严重呼吸道感染和住院的首要原因.
- 婴儿,幼儿和老年人特别容易患RSV相关并发症.
研究的目的:
- 系统地审查和总结德国所有年龄组的RSV的流行病学和经济负担.
- 确定有关RSV对特定人群影响的数据缺口.
主要方法:
- 对2003年至2023年间发表的全文文章进行系统的文献搜索.
- 提取有关发病率,住院,ICU入院,临床特征,季节性,医疗保健资源使用和成本的数据.
- 在选了315个潜在来源后,包括了42篇文章.
主要成果:
- 在儿科和成人住院患者设置中,RSV检测率差异很大 (2.9-55.4%).
- 婴儿和幼儿的负担一直是最高的.
- 对于门诊环境,健康儿童和老年人的数据有限.
结论:
- 在德国,RSV带来了相当大的疾病负担,婴儿受到了不成比例的影响.
- 需要更多地关注RSV对健康儿童和老年人的医疗和经济影响.
- 进一步的研究应解决针对特定人群的现有数据限制.
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