在不同妊娠年龄的早产婴儿中补充铁的效果
Sufeng Ruan1, Jinrong Li1, Fei Xiong1
1Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, China.
BMC pediatrics
|August 20, 2024
概括
补充铁可以有效地减少早产婴儿的铁缺乏症. 然而,早产婴儿的铁含量较低,这表明需要根据个体因素量身定制的补充策略.
科学领域:
- 新生儿营养新生儿营养
- 儿科血液学 儿科血液学
- 营养缺乏症 营养缺乏症
背景情况:
- 缺铁 (ID) 是早产儿最常见的营养缺乏症,影响生长和发育.
- 适当的铁补充对于早产婴儿的身体和神经发展至关重要.
- 这项研究调查了接受标准铁补充剂的早产婴儿的铁状况和生长情况.
研究的目的:
- 评估当前的铁补充是否会导致晚期早产婴儿的铁过载.
- 为了确定当前的铁补充是否满足早产早产婴儿的追赶增长需求.
- 为了比较早期和晚期早产婴儿之间的铁缺乏率,铁状况和身体成长.
主要方法:
- 一项涉及177名早产婴儿 (2020年1月至8月) 的前性后续研究.
- 婴儿被分为早期早产 (<34周) 和晚期早产 (≥34至<37周) 组.
- 在接受 2-4 mg/kg/d 铁补充剂的婴儿中,铁缺乏,铁状况和身体成长的比较.
主要成果:
- 在这两组中,补充铁剂显著降低了缺铁的患病率.
- 早期早产婴儿的费里水平较低 (36.87 ng/ml) 比晚期早产婴儿 (65.78 ng/ml) 在3个月的校正年龄 (p<0.05).
- 较高的出生体重与费里水平有正相关,表明其对铁代谢的影响.
结论:
- 产后补充铁 (2-4 mg/kg/d) 有效地降低了早产婴儿的ID发病率.
- 早期和晚期早产婴儿之间存在铁含量显著差异.
- 建议制定量身定制的铁补充计划,考虑生长,出生体重和妊娠年龄.
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