贝希特病与牙周病之间可能存在关联
Fikriye Orduyilmaz1, Nurdan Ozmeric2, Serenay Elgun3
1Topraklik Oral and Dental Health Center, Ankara, Turkey.
BMC oral health
|August 20, 2024
概括
贝切特病 (BD) 患有牙周炎的患者表现出唾液中白内素-1β (IL-1β) 的升高和氧化 (NO) 的降低. 在BD患者的牙周炎中,牙裂液中的NO含量较高,这表明口腔炎症发生了变化.
科学领域:
- 口腔医学是指口腔医学.
- 免疫学 免疫学 免疫学
- 牙周病学 牙周病学
背景情况:
- 贝切特病 (BD) 是一种多系统性炎症性疾病.
- 牙周病涉及牙和牙支结构的炎症.
- 这两种情况都有共同的炎症途径.
研究的目的:
- 为了研究贝塞特病和牙周病之间的关系.
- 为了比较BD患者和对照者的口腔炎症标志物的水平.
- 分析瘤坏死因子-α (TNF-α),介素-1β (IL-1β) 和氧化物 (NO) 在牙裂液 (GCF) 和唾液中.
主要方法:
- 研究了40名患有牙周炎/牙周炎的BD患者和47名患有牙周炎/牙周炎的对照患者.
- 使用标准临床指数评估牙周状况.
- 收集的GCF和唾液样本用于分析NO,IL-1β和TNF-α.
主要成果:
- 与对照组相比,BD牙炎患者的唾液IL-1β升高 (p=0.045) 和NO降低 (p=.000).
- 在患有牙周炎的BD患者中,GCF NO水平较高 (p=.009).
- 血管干扰的BD患者的唾液NO水平较低 (p=.000).
结论:
- 在患有牙周炎的BD患者中,唾液IL-1β升高和NO降低表明口腔炎发生变化.
- 这些发现突出了与BD严重程度和参与相关的口腔炎症特征.
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