在腹腔镜手术中为减轻疼痛而添加氧化和氧气到二氧化碳肺上:双盲随机对照试验
Jasper Verguts1,2, Eline Soors3,4, Ina Callebaut2,4
1Department of Obstetrics and Gynaecology, Jessa Hospital, Hasselt, Belgium.
BJOG : an international journal of obstetrics and gynaecology
|August 21, 2024
概括
改变的灌气气体混合物在妇科腹腔镜手术中没有减少术后疼痛. 这项研究发现,与标准的二氧化碳 (CO2) 灌气相比,疼痛强度或阿片类药物使用没有显著差异.
科学领域:
- 妇科手术手术是妇科手术.
- 腹腔镜手术的方法 腹腔镜手术
- 疼痛管理 疼痛管理
背景情况:
- 手术后的疼痛是腹腔镜手术后的一个重要问题.
- 标准的灌气气体是100%的二氧化碳 (CO2).
- 正在探索改变的气体混合物,以潜在地减轻疼痛.
研究的目的:
- 为了评估是否改变了吸气气体混合物 (86% CO2,10% N2O,4% O2) 减少术后疼痛的强度.
- 为了比较改变气体混合物的疗效与妇科腹腔镜手术中的标准100%CO2灌注.
主要方法:
- 潜在的,随机的,双盲的,优越性试验.
- 74名接受选择性妇科腹腔镜手术的患者被随机分类.
- 疼痛评估使用11点数值评分尺度在4,8,24小时和术后7天.
主要成果:
- 在任何时间点,改变气体组和100%CO2组之间的术后疼痛得分没有显著差异.
- 在前24小时内静脉注射皮里特拉米德的总消费量在两组之间没有显著差异.
结论:
- 与100%的CO2相比,经测试的替代灌气气体混合物没有减少手术后的疼痛.
- 目前的证据不支持在妇科腹腔镜手术中使用这种特定的改变气体混合物来减轻疼痛.
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
66
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
66
Skeletal Muscle Relaxants: Therapeutic Uses
477
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
477
General Anesthesia: Overview
199
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
199
Local Anesthetics: Clinical Application as Epidural Anesthesia
423
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
423
Local Anesthetics: Clinical Application as Spinal Anesthesia
594
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
594


