在英国兽医实践提交的临床实验室样本中,对牛呼吸系统疾病病原体的相对频率进行了回顾性研究
Katharine Denholm1, Neil P Evans1, Katharine Baxter-Smith2
1School of Biodiversity, One Health and Veterinary Medicine, University of Glasgow, Glasgow, UK.
The Veterinary record
|August 21, 2024
概括
在英国,牛呼吸道疾病 (BRD) 往往涉及多种病原体,一些与BRD不太相关的病毒普遍存在. 温暖的月份显示,牛中某些病原体诱导的呼吸道疾病的几率较低.
科学领域:
- 兽医微生物学 兽医微生物学
- 动物流行病学动物流行病学
- 病原体监测 病原体监测 病原体监测
背景情况:
- 牛呼吸道疾病 (BRD) 是牛畜牧业的一个重大问题.
- 了解病原体的流行和季节性对于有效的疾病管理至关重要.
- 以前的研究集中在特定的病原体上,但需要对临床样本进行更广泛的分析.
研究的目的:
- 调查英国牛呼吸道病原体的相对频率和季节性.
- 分析用于实验室PCR测试的临床病例提交,以确定常见和新出现的病原体.
- 评估病原体检测和牛的季节之间的关联.
主要方法:
- 来自英国95家兽医诊所的407个组合临床样本的回顾性分析 (2020年11月 - 2022年9月).
- 使用实验室PCR测试来识别病原体.
- 采用描述性空间分析,奇平方,波桑和后勤回归建模.
主要成果:
- 高比例的样本 (77.6%) 对多种细菌物种呈阳性,而17.7%对多种病毒呈阳性.
- 与较冷的月份相比,温暖的月份 (三月至八月) 与某些病原体引起的呼吸道疾病的几率明显较低有关.
- 牛类冠状病毒,通常不被认为是英国的主要BRD病原体,被发现是普遍存在的.
结论:
- 在英国,大多数临床BRD样本都是多病原性.
- 牛冠状病毒似乎是临床BRD病例中普遍存在的病原体.
- 该研究强调了BRD病因的复杂性以及需要全面的诊断方法.
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